We start with our revolutionary wide high-tension range and corrector-ready platform, combined with a wide pole piece gap delivering the space to do more. With strong support from Zhixin Wang and Sen‐Fang Sui, Shi turned to the Tsinghua University administration for help in early May 2008. Seeing as how Krios is the god of constellations and his name means Ram (or The Ram) Krios is closely associated with the constellation Aries which is a Ram. Additionally, acquired data can be evaluated through on-the-fly monitoring of data quality and optimizing acquisition parameters as needed.The Thermo Scientific Krios Rx Cryo-TEM is the flagship of the iSPA Workflow, the first pharma-dedicated solution for single particle analysis (SPA) and structure-based drug design. This high-end microscope is optimized for the drug discovery process with a throughput of over 400 high-quality images per hour. The innovative enclosed platform combines excellent optical performance and thermal and mechanical stability with a high throughput sample loader. This can be further improved with the Thermo Scientific Falcon 4 Detector and the Thermo Scientific Phase Plate Solution.Solve more structures more easily at higher resolution with the next-generation Thermo Scientific Krios G4 Cryo-TEM.Presented by: Dr. Marc Storms Product Marketing Manager, Thermo Fisher ScientificSolve more structures more easily at higher resolution with the next-generation Thermo Scientific Krios G4 Cryo-TEM.Presented by: Dr. Marc Storms Product Marketing Manager, Thermo Fisher ScientificCryo-electron microscopy enables the structural analysis of challenging biological targets such as large complexes, flexible species and membrane protein.Learn how to take advantage of rational drug design for many more major drug target classes, leading to best-in-class drugs.Cryo-EM techniques enable multiscale observations of 3D biological structures in their near-native states, informing faster, more efficient development of therapeutics.Single particle analysis (SPA) is a cryo-electron microscopy technique that enables structural characterization at near-atomic resolutions, unraveling dynamic biological processes and the structure of biomolecular complexes/assemblies.Cryo-electron tomography (cryo-ET) delivers both structural information about individual proteins as well as their spatial arrangements within the cell. With this method, atomic details can be extracted from individual nanocrystals (<200 nm in size), even in a heterogeneous mixture.To ensure optimal system performance, we provide you access to a world-class network of field service experts, technical support, and certified spare parts. The Titan Krios is the most powerful and flexible high resolution electron microscope for 3D characterization of biologicals samples. Choose from a broad variety of detector and software options to configure the Krios TEM for any of these applications:The Thermo Scientific Krios S/TEM platform is constantly evolving, and is now the world's most powerful, commercially- available suite of S/TEM solutions for Life Sciences. Cryo-ET can bridge the gap between light microscopy and near-atomic-resolution techniques like single-particle analysis.MicroED is an exciting new technique with applications in the structural determination of small molecules and protein.
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